Free Web Site - Free Web Space and Site Hosting - Web Hosting - Internet Store and Ecommerce Solution Provider - High Speed Internet
Search the Web

Symptoms

Of

 

Trichothecene Mycotoxin

(T-2 toxin, and other Trichothecenes)

Exposure

 

Part Two

 

With

Bibliography

 

(HOME)

 

Compiled by

Deborah Cazden

April 22, 2001

 

 

Sources:

http://www.rand.org/publications/MR/MR1018.5/index.html

http://www.doh.wa.gov/ehp/oehas/mold.html

 

Please feel free to use this resource.

All I ask is to please keep my name on it, present it

as a whole document, and do not use it for profit.

Thank You.

 

 

© 2001 Deborah Cazden

All rights reserved

kieoh@visto.com

 

 

Disclaimer,

 This document is not meant to diagnose a health problem it is simply a tool.  Please consult with your regular doctor if you have a health concern.  No guarantee is implied by the use of this document.  All information contained here is accurate to the best of my knowledge, but since the compilation is from other sources, I cannot guarantee all the information is correct.


 


 

 

 

 

 

 

 


N
A                                         SYMPTOM (description)
M                                          (references)
E


 

 

 

 

 

 

63.     Eye pain 
(Watson, Mirocha, and Hayes, 1984).

 

 

 

 

 

 

64.     Eyelid edema (swelling of the eyelid)
(Bunner, 1983).

 

 

 

 

 

 

65.     Fatigue 
(Haig, 1982; Schultz, 1982; Crossland and Townsend, 1984).

 

 

 

 

 

 

66.     Fetal abnormalities 
(Haig, 1982; Schultz, 1982; Watson, Mirocha, and Hayes, 1984; Stahl et al., 1985; Crossland and Townsend, 1984).

 

 

 

 

 

 

67.     Fever
 (Belt et al., 1979; Murphy et al., 1978; Yap, et al., 1979; Diggs et al., 1978; Bukowski et al., 1982; Thigpen et al., 1981; Crossland and Townsend, 1984).

 

 

 

 

 

 

68.     Fibrinous exudate (fibrin escaping from the blood vessels)
 (Goodwin et al., 1981).

 

 

 

 

 

 

69.     Gastroenteritis (acute inflammation of the lining of the stomach and intestines)
 (Wannemacher and Wiener, 1997).

 

 

 

 

 

 

70.     Gastrointestinal toxicity
 (Watson, Mirocha, and Hayes, 1984; Bunner et al., 1985; and Wannemacher and Wiener, 1997).

 

 

 

 

 

 

71.     Gastrointestinal tract necrosis (toxicity of the stomach and intestines)
 (Coppock et al., 1985)

 

 

 

 

 

 

72.     Hallucinations  (false perception of sight, hearing, smell, taste, or touch)
(Belt et al., 1979; Murphy et al., 1978; Yap, et al., 1979; Diggs et al., 1978; Bukowski et al., 1982; Thigpen et al., 1981; Crossland and Townsend, 1984).

 

 

 

 

 

 

73.     Headaches 
(Croft et al.,1986; Jarvis, 1985)

 

 

 

 

 

 

74.     Hematemesis  (throwing up blood)
(Haig, 1982; Schultz, 1982; Crossland and Townsend, 1984).

 

 

 

 

 

 

75.     Hematological toxicity (blood toxicity)
 (Watson, Mirocha, and Hayes, 1984; Bunner et al., 1985; and Wannemacher and Wiener, 1997).

 

 

 

 

 

 

76.     Hemorrhagic bullae (large blisters that pop easily)
 (Wannemacher and Wiener, 1997).

 

 

 

 

 

 

77.     Hemorrhagic diathesis (bleeding tendency)
 (Ueno et al., 1984).

 

 

 

 

 

 

78.     Hemorrhagic foci (group of cells prone to hemorrhaging)
 (Ueno et al., 1984; Stahl et al., 1985),

 

 

 

 

 

 

79.     Hemoptysis  (spitting up blood)
(Stahl, Green, and Farnum, 1985).

 

 

 

 

 

 

80.     Hyperglycemia (too much sugar in the blood)
(Coppock et al., 1985)

 

 

 

 

 

 

81.     Hyperpigmentation (unusual skin darkening in a specific area)
 (Wannemacher and Wiener, 1997).

 

 

 

 

 

 

82.     Hypotension (low blood pressure)
 (Haig, 1982; Schultz, 1982; Crossland and Townsend, 1984).

 

 

 

 

 

 

83.     Hypothermia  (low body temperature)
 (Wannemacher and Wiener, 1997).
 


 

 

 

 

 

 

 


N
A                                         SYMPTOM (description)
M                                          (references)
E


 

 

 

 

 

 

84.     Hypoxia (low oxygen in the arteries)
 (Rukmini, Prasad, and Rao, 1980; Lutsky et al., 1978; Bunner, 1983; Bunner et al. 1985).

 

 

 

 

 

 

85.     Immunosupression (immune system dysfunction)
 (Ueno, 1983; Yarom et al., 1984; Jagadeesan et al., 1982).

 

 

 

 

 

 

86.     Impairment of ribosome function
 (NAS, 1983; Coulombe, 1993; Tutelyan and Kravchenko, 1981)

 

 

 

 

 

 

87.     Impotence  (inability to achieve erection or ejaculation)
(Haig, 1982; Schultz, 1982; Watson, Mirocha, and Hayes, 1984; Stahl et al., 1985; Crossland and Townsend, 1984).

 

 

 

 

 

 

88.     Increased partial thromboplastin times blood test
 (Yarom et al., 1984).

 

 

 

 

 

 

89.     Increased prothrombin times (increased clotting time)
(Yarom et al., 1984).

 

 

 

 

 

 

90.     Increased vascular fragility (blood vessels are more fragile)
 (Smith and Moss, 1985).

 

 

 

 

 

 

91.    Induction of reparable single strand DNA breaks 

 

 

 

 

 

 

92.     Inhibition of mitochondrial protein synthesis
 (Pace et al., 1985)

 

 

 

 

 

 

93.     Inhibition of platelet aggregation
 (Yarom et al., 1984).

 

 

 

 

 

 

94.     Inhibition of protein synthesis
 (Ueno, 1983; Ueno et al., 1984; Tutelyan and Kravchenko, 1981)

 

 

 

 

 

 

95.     Inhibition of thiol enzymes
 (Tutelyan and Kravchenko, 1981; Ueno et al., 1984)

 

 

 

 

 

 

96.     Inhibition on DNA synthesis
 (Thompson and Wannemacher, 1984)

 

 

 

 

 

 

97.     Interstitial myocardial hemorrhage (hemmhorage in between the myocardium)
 (Stahl, Green, and Farnum, 1985).

 

 

 

 

 

 

98.     Itching
 (Watson, Mirocha, and Hayes, 1984).

 

 

 

 

 

 

99.     Jaundice (yellowing of the skin and eyes from excess bilirubin in the blood)
 (Stahl, Green, and Farnum, 1985).

 

 

 

 

 

 

100.  Joint pain
 (Haig, 1982; Schultz, 1982; Crossland and Townsend, 1984).

 

 

 

 

 

 

101.  Leukopenia (shortage of white blood cells)
 (Ueno et al., 1984).

 

 

 

 

 

 

102.  Lymphatic changes (changes in the lymph system)
 (Schiefer, 1984; Wannemacher et al., 1983).

 

 

 

 

 

 

103.  Malaise (vague feeling of discomfort, or that something is not right)
 (Thigpen et al., 1981; Yap et al., 1979; Croft et al., 1986; Watson, Mirocha, and Hayes, 1984; Crossland and Townsend, 1984)

 

 

 

 

 

 

104.  Melena (blood in the stool)
 (Wannemacher and Wiener, 1997).


 

 

 

 

 

 

 

N
A                                         SYMPTOM (description)
M                                          (references)
E

 

 

 

 

 

 

105.  Memory loss 
(Belt et al., 1979; Murphy et al., 1978; Yap, et al., 1979; Diggs et al., 1978; Bukowski et al., 1982; Thigpen et al., 1981; Crossland and Townsend, 1984).

 

 

 

 

 

 

106.  Memory problems
 (Haig, 1982; Schultz, 1982; Crossland and Townsend, 1984).

 

 

 

 

 

 

107.  Meningeal bleeding (bleeding in the meninges of the brain)
 (Ueno et al., 1984).

 

 

 

 

 

 

108.  Micronodular cirrhosis  (complication of liver disease)
(Stahl, Green, and Farnum, 1985).

 

 

 

 

 

 

109.  Muscle injury
 (Bunner, 1983).

 

 

 

 

 

 

110.  Myelosuppression  (suppression of bone marrow activity)
(Wannemacher and Wiener, 1997).

 

 

 

 

 

 

111.  Nasal itching
(Rukmini, Prasad, and Rao, 1980; Lutsky et al., 1978; Bunner, 1983; Bunner et al. 1985).

 

 

 

 

 

 

112.  Nasal stuffiness
 (Bell, et al., 1993a; Bell et al., 1993b)

 

 

 

 

 

 

113.  Nausea
 (Ueno et al., 1984).

 

 

 

 

 

 

114.  Neuropsychiatric manifestations (neurobiological brain disorders)
 (Forgacs, 1972)

 

 

 

 

 

 

115.  Neurotoxic  (brain and nerve toxin)
(Thigpen et al., 1981; Yap et al., 1979; Croft et al., 1986; Watson, Mirocha, and Hayes, 1984; Crossland and Townsend, 1984)

 

 

 

 

 

 

116.  Numbness
 (Schiefer and Hancock, 1984; Murphy et al., 1978; Bukowski et al., 1982; Diggs et al., 1978; Belt et al., 1979; Yap et al., 1979; Thigpen et al., 1981; Goodwin et al., 1981).

 

 

 

 

 

 

117.  Oral mucosal necrosis (death of tissue in the mouth)
 (Mayer 1953a, 1953b)

 

 

 

 

 

 

118.  Orthostatic hypotension  (low blood pressure when lying down)
(Yap et al., 1979; Thigpen et al., 1981; Murphy et al., 1978; Bukowski et al., 1982).

 

 

 

 

 

 

119.  Pain
 (Wannemacher and Wiener, 1997).

 

 

 

 

 

 

120.  Pancreatic damage
 (Coppock et al., 1985)

 

 

 

 

 

 

121.  Paresthesia (abnormal sensations, such as numbness, tingling, or burning )
(Otto et al., 1989)

 

 

 

 

 

 

122.  Petechial rashes (rash caused by bleeding under the skin)
 (Ueno et al., 1984).

 

 

 

 

 

 

123.  Prolonged rashes
 (Schultz, 1982)

 

 

 

 

 

 

124.  Pulmonary collapse (lung collapse)
 (Rukmini, Prasad, and Rao, 1980; Lutsky et al., 1978; Bunner, 1983; Bunner et al. 1985).

 

 

 

 

 

 

125.  Pulmonary consolidation
(Rukmini, Prasad, and Rao, 1980; Lutsky et al., 1978; Bunner, 1983; Bunner et al. 1985).